KEGG   NETWORK: N00702
Entry
N00702                      Network                                
Name
Tetrahydrobiopterin biosynthesis, GTP to BH4
Definition
GTP -- GCH1 >> PTS >> SPR -> BH4
  Expanded
C00044 -- 2643 >> 5805 >> 6697 -> C00272
Class
nt06016 Phenylalanine and tyrosine metabolism
nt06028 Dopamine and serotonin metabolism
Type
Reference
Pathway
hsa00790  Folate biosynthesis
Gene
2643  GCH1; GTP cyclohydrolase 1
5805  PTS; 6-pyruvoyltetrahydropterin synthase
6697  SPR; sepiapterin reductase
Metabolite
C00044  GTP
C00272  Tetrahydrobiopterin
Reference
  Authors
Thony B, Auerbach G, Blau N
  Title
Tetrahydrobiopterin biosynthesis, regeneration and functions.
  Journal
Biochem J 347 Pt 1:1-16 (2000)
DOI:10.1042/bj3470001
Reference
  Authors
Sumi-Ichinose C, Ohtsuki M, Shiraishi H, Nomura T
  Title
[Perspectives on tetrahydrobiopterin research].
  Journal
Nihon Yakurigaku Zasshi 118:371-7 (2001)
DOI:10.1254/fpj.118.371
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