KEGG   NETWORK: N00832
Entry
N00832                      Network                                
Name
Branched-chain amino acids degradation
Definition
Leu,Val,Ile -- BCAT1/2 >> (BCKDHA+BCKDHB+DBT+DLD) -> IV-CoA,IB-CoA,2-MB-CoA
  Expanded
(C00123,C00183,C00407) -- (586,587) >> (593+594+1629+1738) -> (C02939,C00630,C15980)
Class
nt06024 Valine, leucine and isoleucine degradation
Type
Reference
Pathway
hsa00280  Valine, leucine and isoleucine degradation
Gene
586  BCAT1; branched chain amino acid transaminase 1
587  BCAT2; branched chain amino acid transaminase 2
593  BCKDHA; branched chain keto acid dehydrogenase E1 subunit alpha
594  BCKDHB; branched chain keto acid dehydrogenase E1 subunit beta
1629  DBT; dihydrolipoamide branched chain transacylase E2
1738  DLD; dihydrolipoamide dehydrogenase
Metabolite
C00123  L-Leucine
C00183  L-Valine
C00407  L-Isoleucine
C02939  3-Methylbutanoyl-CoA
C00630  2-Methylpropanoyl-CoA
C15980  (S)-2-Methylbutanoyl-CoA
LinkDB

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