| Entry |
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| Name |
Yersinia YopM to Pyrin Inflammasome signaling pathway
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| Definition |
YopM -> (PKN1,PKN2) -| (MEFV+PYCARD) |
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| Expanded |
K23478 -> (5586,5585) -| (4210+29108) |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 5586 | PKN2; protein kinase N2 |
| 5585 | PKN1; protein kinase N1 |
| 4210 | MEFV; MEFV innate immuity regulator, pyrin |
| 29108 | PYCARD; PYD and CARD domain containing |
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| Perturbant |
| K23478 (YopM) | yopM; outer membrane protein YopM |
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| Reference |
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| Authors |
Chung LK, Park YH, Zheng Y, Brodsky IE, Hearing P, Kastner DL, Chae JJ, Bliska JB |
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| Title |
The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome. |
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| Journal |
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| Reference |
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| Authors |
Ratner D, Orning MP, Proulx MK, Wang D, Gavrilin MA, Wewers MD, Alnemri ES, Johnson PF, Lee B, Mecsas J, Kayagaki N, Goguen JD, Lien E |
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| Title |
The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation. |
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| Journal |
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| LinkDB |
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