| Entry |
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| Name |
Mutation-caused aberrant SNCA to L-DOPA generation
|
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| Definition |
SNCA* // TH -> L-Dopa |
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| Expanded |
6622v1 // 7054 -> C00355 |
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| Class |
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| Type |
Variant
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| Pathway |
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| Disease |
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| Gene |
| 6622 | SNCA; synuclein alpha |
| 7054 | TH; tyrosine hydroxylase |
|
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| Variant |
|
|---|
| Metabolite |
| C00355 | 3,4-Dihydroxy-L-phenylalanine |
|
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| Reference |
|
|---|
| Authors |
Perez RG, Waymire JC, Lin E, Liu JJ, Guo F, Zigmond MJ |
|---|
| Title |
A role for alpha-synuclein in the regulation of dopamine biosynthesis. |
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| Journal |
|
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| Reference |
|
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| Authors |
Perez RG, Hastings TG |
|---|
| Title |
Could a loss of alpha-synuclein function put dopaminergic neurons at risk? |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Jesko H, Lenkiewicz AM, Wilkaniec A, Adamczyk A |
|---|
| Title |
The interplay between parkin and alpha-synuclein; possible implications for the pathogenesis of Parkinson's disease. |
|---|
| Journal |
Acta Neurobiol Exp (Wars) 79:276-289 (2019) |
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| LinkDB |
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