| Entry |
|
| Name |
Yersinia YopH to TCR-NFAT signaling pathway
|
| Definition |
YopH -| (SLP76,LAT,VAV) |
| Expanded |
K23474 -| (3937,27040,(7409,7410,10451)) |
| Class |
|
| Type |
Pathogen
|
| Pathway |
|
| Disease |
|
| Gene |
| 3937 | LCP2; lymphocyte cytosolic protein 2 |
| 27040 | LAT; linker for activation of T cells |
| 7409 | VAV1; vav guanine nucleotide exchange factor 1 |
| 7410 | VAV2; vav guanine nucleotide exchange factor 2 |
| 10451 | VAV3; vav guanine nucleotide exchange factor 3 |
|
| Perturbant |
| K23474 (YopH) | yopH; tyrosine-protein phosphatase YopH |
|
| Reference |
|
| Authors |
Gerke C, Falkow S, Chien YH |
| Title |
The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation. |
| Journal |
|
| Reference |
|
| Authors |
Rolan HG, Durand EA, Mecsas J |
| Title |
Identifying Yersinia YopH-targeted signal transduction pathways that impair neutrophil responses during in vivo murine infection. |
| Journal |
|
| LinkDB |
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