Entry |
|
Name |
Yersinia YopH to TCR-NFAT signaling pathway
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Definition |
YopH -| (SLP76,LAT,VAV) |
Expanded |
K23474 -| (3937,27040,(7409,7410,10451)) |
Class |
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Type |
Pathogen
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Pathway |
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Disease |
|
Gene |
3937 | LCP2; lymphocyte cytosolic protein 2 |
27040 | LAT; linker for activation of T cells |
7409 | VAV1; vav guanine nucleotide exchange factor 1 |
7410 | VAV2; vav guanine nucleotide exchange factor 2 |
10451 | VAV3; vav guanine nucleotide exchange factor 3 |
|
Perturbant |
K23474 (YopH) | yopH; tyrosine-protein phosphatase YopH |
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Reference |
|
Authors |
Gerke C, Falkow S, Chien YH |
Title |
The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation. |
Journal |
|
Reference |
|
Authors |
Rolan HG, Durand EA, Mecsas J |
Title |
Identifying Yersinia YopH-targeted signal transduction pathways that impair neutrophil responses during in vivo murine infection. |
Journal |
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LinkDB |
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