| Entry |
|
|---|
| Name |
Scrapie conformation PrPSc to Notch singling pathway
|
|---|
| Definition |
PRNP* -> NOTCH1 |
|---|
| Expanded |
5621v1 -> 4851 |
|---|
| Class |
|
|---|
| Type |
Variant
|
|---|
| Pathway |
|
|---|
| Disease |
|
|---|
| Gene |
| 4851 | NOTCH1; notch receptor 1 |
|
|---|
| Variant |
5621v1 (PRNP*) PRNP scrapie conformation
|
|---|
| Reference |
|
|---|
| Authors |
Ishikura N, Clever JL, Bouzamondo-Bernstein E, Samayoa E, Prusiner SB, Huang EJ, DeArmond SJ |
|---|
| Title |
Notch-1 activation and dendritic atrophy in prion disease. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Dearmond SJ, Bajsarowicz K |
|---|
| Title |
PrPSc accumulation in neuronal plasma membranes links Notch-1 activation to dendritic degeneration in prion diseases. |
|---|
| Journal |
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|---|
| LinkDB |
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|---|
