KEGG   NETWORK: N01390
Entry
N01390                      Network                                
Name
p,p'-DDT to SOD/Cat-mediated ROS neutralization
Definition
DDT -| SOD1
  Expanded
C04623 -| 6647
Class
nt06253 Antioxidant system (cancer)
Type
Env factor
Pathway
hsa05208  Chemical carcinogenesis - reactive oxygen species
Disease
H00048  Hepatocellular carcinoma
H00020  Colorectal cancer
Gene
6647  SOD1; superoxide dismutase 1
Perturbant
C04623 (DDT)  DDT
Reference
  Authors
Jin X, Chen M, Song L, Li H, Li Z
  Title
The evaluation of p,p'-DDT exposure on cell adhesion of hepatocellular carcinoma.
  Journal
Toxicology 322:99-108 (2014)
DOI:10.1016/j.tox.2014.05.002
Reference
  Authors
Song L, Zhao J, Jin X, Li Z, Newton IP, Liu W, Xiao H, Zhao M
  Title
The organochlorine p,p'-dichlorodiphenyltrichloroethane induces colorectal cancer growth through Wnt/beta-catenin signaling.
  Journal
Toxicol Lett 229:284-91 (2014)
DOI:10.1016/j.toxlet.2014.06.003
Reference
  Authors
Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT
  Title
Application of the key characteristics of carcinogens in cancer hazard identification.
  Journal
Carcinogenesis 39:614-622 (2018)
DOI:10.1093/carcin/bgy031
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