KEGG   NETWORK: N01458
Entry
N01458                      Network                                
Name
BMP-HAMP signaling pathway
Definition
BMP2/6 -> ((ACVR2B,BMPR2)+(ACVR1,BMPR1A) -> (SMAD1,SMAD5,SMAD9) == SMAD4 => HAMP
  Expanded
(650,654) -> ((93,659)+(90,657) -> (4086,4090,4093) == 4089 => 57817
Class
nt06507 TGFB signaling
Type
Reference
Pathway
hsa04350  TGF-beta signaling pathway
Gene
650  BMP2; bone morphogenetic protein 2
654  BMP6; bone morphogenetic protein 6
93  ACVR2B; activin A receptor type 2B
659  BMPR2; bone morphogenetic protein receptor type 2
90  ACVR1; activin A receptor type 1
657  BMPR1A; bone morphogenetic protein receptor type 1A
4086  SMAD1; SMAD family member 1
4090  SMAD5; SMAD family member 5
4093  SMAD9; SMAD family member 9
4089  SMAD4; SMAD family member 4
57817  HAMP; hepcidin antimicrobial peptide
Reference
PMID:30420953
  Authors
Pantopoulos K
  Title
Inherited Disorders of Iron Overload.
  Journal
Front Nutr 5:103 (2018)
DOI:10.3389/fnut.2018.00103
Reference
PMID:32258529
  Authors
Piperno A, Pelucchi S, Mariani R
  Title
Inherited iron overload disorders.
  Journal
Transl Gastroenterol Hepatol 5:25 (2020)
DOI:10.21037/tgh.2019.11.15
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