| Entry |
|
|---|
| Name |
DNA degradation by extracellular/endolysosomal DNAse
|
|---|
| Definition |
(TREX1,DNASE1,DNASE2) -| DNA |
|---|
| Expanded |
(11277,(1773,1774,1775,1776),(1777,58511)) -| C00039 |
|---|
| Class |
|
|---|
| Type |
Reference
|
|---|
| Pathway |
|
|---|
| Gene |
| 11277 | TREX1; three prime repair exonuclease 1 |
| 1773 | DNASE1; deoxyribonuclease 1 |
| 1774 | DNASE1L1; deoxyribonuclease 1 like 1 |
| 1775 | DNASE1L2; deoxyribonuclease 1 like 2 |
| 1776 | DNASE1L3; deoxyribonuclease 1 like 3 |
| 1777 | DNASE2; deoxyribonuclease 2, lysosomal |
| 58511 | DNASE2B; deoxyribonuclease 2 beta |
|
|---|
| Metabolite |
|
|---|
| Reference |
|
|---|
| Authors |
Santa P, Garreau A, Serpas L, Ferriere A, Blanco P, Soni C, Sisirak V |
|---|
| Title |
The Role of Nucleases and Nucleic Acid Editing Enzymes in the Regulation of Self-Nucleic Acid Sensing. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Motwani M, Pesiridis S, Fitzgerald KA |
|---|
| Title |
DNA sensing by the cGAS-STING pathway in health and disease. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Simpson SR, Hemphill WO, Hudson T, Perrino FW |
|---|
| Title |
TREX1 - Apex predator of cytosolic DNA metabolism. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
