KEGG   NETWORK: N01588
Entry
N01588                      Network                                
Name
Fe3+ Ferritin transport
Definition
ATG5/7 -> NCOA4 -- (Fe3++(FTH1+FTL))
  Expanded
(9474+10533) -> 8031 -- (C14819+(2495+2512))
Class
nt06525 Ferroptosis
Type
Reference
Pathway
hsa04216  Ferroptosis
Gene
9474  ATG5; autophagy related 5
10533  ATG7; autophagy related 7
8031  NCOA4; nuclear receptor coactivator 4
2495  FTH1; ferritin heavy chain 1
2512  FTL; ferritin light chain
Metabolite
C14819  Fe3+
Reference
  Authors
Santana-Codina N, Mancias JD
  Title
The Role of NCOA4-Mediated Ferritinophagy in Health and Disease.
  Journal
Pharmaceuticals (Basel) 11:ph11040114 (2018)
DOI:10.3390/ph11040114
Reference
  Authors
Ajoolabady A, Aslkhodapasandhokmabad H, Libby P, Tuomilehto J, Lip GYH, Penninger JM, Richardson DR, Tang D, Zhou H, Wang S, Klionsky DJ, Kroemer G, Ren J
  Title
Ferritinophagy and ferroptosis in the management of metabolic diseases.
  Journal
Trends Endocrinol Metab 32:444-462 (2021)
DOI:10.1016/j.tem.2021.04.010
Reference
  Authors
Bayir H, Anthonymuthu TS, Tyurina YY, Patel SJ, Amoscato AA, Lamade AM, Yang Q, Vladimirov GK, Philpott CC, Kagan VE
  Title
Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis.
  Journal
Cell Chem Biol 27:387-408 (2020)
DOI:10.1016/j.chembiol.2020.03.014
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