KEGG   NETWORK: N01649
Entry
N01649                      Network                                
Name
Ca2+/CAM-VGCC/RYR signaling pathway
Definition
Ca2+(cyto) == CALM == (CAV,RYR)
  Expanded
C00076 == (801,805,808) == ((779,775,773,774,777),(6261,6262,6263))
Class
nt06528 Calcium signaling
Type
Reference
Gene
801  CALM1; calmodulin 1
805  CALM2; calmodulin 2
808  CALM3; calmodulin 3
779  CACNA1S; calcium voltage-gated channel subunit alpha1 S
775  CACNA1C; calcium voltage-gated channel subunit alpha1 C
773  CACNA1A; calcium voltage-gated channel subunit alpha1 A
774  CACNA1B; calcium voltage-gated channel subunit alpha1 B
777  CACNA1E; calcium voltage-gated channel subunit alpha1 E
6261  RYR1; ryanodine receptor 1
6262  RYR2; ryanodine receptor 2
6263  RYR3; ryanodine receptor 3
Metabolite
C00076  Calcium cation
Reference
  Authors
Tidow H, Nissen P
  Title
Structural diversity of calmodulin binding to its target sites.
  Journal
FEBS J 280:5551-65 (2013)
DOI:10.1111/febs.12296
Reference
  Authors
Kovalevskaya NV, van de Waterbeemd M, Bokhovchuk FM, Bate N, Bindels RJ, Hoenderop JG, Vuister GW
  Title
Structural analysis of calmodulin binding to ion channels demonstrates the role of its plasticity in regulation.
  Journal
Pflugers Arch 465:1507-19 (2013)
DOI:10.1007/s00424-013-1278-0
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