KEGG   NETWORK: N01669
Entry
N01669                      Network                                
Name
Blood group A/B Lewis y antigen biosynthesis
Definition
[TypeIIA,TypeIIB] -- FUT3*Le -> [ALey,BLey]
  Expanded
[G00054,G00052] -- 2525v1 -> [G00734,G01439]
Class
nt06035 Blood group carbohydrate antigen biosynthesis
Type
Reference
Pathway
hsa00601  Glycosphingolipid biosynthesis - lacto and neolacto series
Gene
2525  FUT3; fucosyltransferase 3 (Lewis blood group)
Variant
2525v1 (FUT3*Le)  FUT3 Le allele
Metabolite
G00054  Type II A antigen
G00052  Type II B antigen
G00734  III3,IV2Fuca,IV3GalNAca-nLc4-Cer
G01439  III3,IV2Fuca,IV3Gala-nLc4-Cer
Reference
PMID:36691627
  Authors
Jajosky RP, Wu SC, Zheng L, Jajosky AN, Jajosky PG, Josephson CD, Hollenhorst MA, Sackstein R, Cummings RD, Arthur CM, Stowell SR
  Title
ABO blood group antigens and differential glycan expression: Perspective on the evolution of common human enzyme deficiencies.
  Journal
iScience 26:105798 (2023)
DOI:10.1016/j.isci.2022.105798
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