KEGG   NETWORK: N01822
Entry
N01822                      Network                                
Name
Linker of nucleoskeleton and cytoskeleton (LINC) complex
Definition
DES == PLEC == (SYNE3,SYNE1,SYNE2) == (SUN,TMEM43,EMD,LBR) == (LMNA+LMNB)
  Expanded
1674 == 5339 == (161176,23345,23224) == ((23353,25777),79188,2010,3930) == (4000+4001,84823)
Class
nt06539 Cytoskeleton in muscle cells
Type
Reference
Pathway
hsa04820  Cytoskeleton in muscle cells
Gene
1674  DES; desmin
5339  PLEC; plectin
161176  SYNE3; spectrin repeat containing nuclear envelope family member 3
23345  SYNE1; spectrin repeat containing nuclear envelope protein 1
23224  SYNE2; spectrin repeat containing nuclear envelope protein 2
23353  SUN1; Sad1 and UNC84 domain containing 1
25777  SUN2; Sad1 and UNC84 domain containing 2
79188  TMEM43; transmembrane protein 43
2010  EMD; emerin
3930  LBR; lamin B receptor
4000  LMNA; lamin A/C
4001  LMNB1; lamin B1
84823  LMNB2; lamin B2
Reference
PMID:24481844
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
PMID:23188744
  Authors
Smith LR, Meyer G, Lieber RL
  Title
Systems analysis of biological networks in skeletal muscle function.
  Journal
Wiley Interdiscip Rev Syst Biol Med 5:55-71 (2013)
DOI:10.1002/wsbm.1197
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