| Entry |
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| Name |
Regulation of VWF-GPIb-IX-V interaction, ADAMTS13
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| Definition |
ADAMTS13 -| VWF -> (GP1BA+GP1BB+GP9+GP5) |
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| Expanded |
11093 -| 7450 -> (2811+2812+2815+2814) |
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| Class |
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| Type |
Reference
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| Gene |
| 11093 | ADAMTS13; ADAM metallopeptidase with thrombospondin type 1 motif 13 |
| 7450 | VWF; von Willebrand factor |
| 2811 | GP1BA; glycoprotein Ib platelet subunit alpha |
| 2812 | GP1BB; glycoprotein Ib platelet subunit beta |
| 2815 | GP9; glycoprotein IX platelet |
| 2814 | GP5; glycoprotein V platelet |
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| Reference |
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| Authors |
Crawley JT, de Groot R, Xiang Y, Luken BM, Lane DA |
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| Title |
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor. |
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| Journal |
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| Reference |
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| Authors |
Ercig B, Arfman T, Hrdinova J, Wichapong K, Reutelingsperger CPM, Vanhoorelbeke K, Nicolaes GAF, Voorberg J |
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| Title |
Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity. |
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| Journal |
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| Reference |
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| Authors |
Petri A, Kim HJ, Xu Y, de Groot R, Li C, Vandenbulcke A, Vanhoorelbeke K, Emsley J, Crawley JTB |
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| Title |
Crystal structure and substrate-induced activation of ADAMTS13. |
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| Journal |
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| LinkDB |
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