KEGG   NETWORK: N01848
Entry
N01848                      Network                                
Name
Membrane-associated periodic skeleton (MPS)
Definition
Actin_ring == ADD1/2/3+TMOD1/2/3 == SPTAN1+SPTBN1/4/5 == ANK3 == (NFASC,SCN8A,KCNQ2/3)
  Expanded
(60,71) == (118,119,120+(7111,29767,29766)) == 6709+6711,57731,51332 == 288 == 23114,6334,3785,3786
Class
nt06541 Cytoskeleton in neurons
Type
Reference
Gene
60  ACTB; actin beta
71  ACTG1; actin gamma 1
118  ADD1; adducin 1
119  ADD2; adducin 2
120  ADD3; adducin 3
7111  TMOD1; tropomodulin 1
29767  TMOD2; tropomodulin 2
29766  TMOD3; tropomodulin 3
6709  SPTAN1; spectrin alpha, non-erythrocytic 1
6711  SPTBN1; spectrin beta, non-erythrocytic 1
57731  SPTBN4; spectrin beta, non-erythrocytic 4
51332  SPTBN5; spectrin beta, non-erythrocytic 5
288  ANK3; ankyrin 3
23114  NFASC; neurofascin
6334  SCN8A; sodium voltage-gated channel alpha subunit 8
3785  KCNQ2; potassium voltage-gated channel subfamily Q member 2
3786  KCNQ3; potassium voltage-gated channel subfamily Q member 3
Reference
  Authors
Lorenzo DN, Edwards RJ, Slavutsky AL
  Title
Spectrins: molecular organizers and targets of neurological disorders.
  Journal
Nat Rev Neurosci 24:195-212 (2023)
DOI:10.1038/s41583-022-00674-6
Reference
  Authors
Costa AR, Sousa MM
  Title
The role of the membrane-associated periodic skeleton in axons.
  Journal
Cell Mol Life Sci 78:5371-5379 (2021)
DOI:10.1007/s00018-021-03867-x
Reference
  Authors
Leterrier C
  Title
The Axon Initial Segment: An Updated Viewpoint.
  Journal
J Neurosci 38:2135-2145 (2018)
DOI:10.1523/JNEUROSCI.1922-17.2018
Reference
  Authors
Mikhaylova M, Rentsch J, Ewers H
  Title
Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines.
  Journal
Cells 9:cells9092006 (2020)
DOI:10.3390/cells9092006
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