KEGG   NETWORK: N01886
Entry
N01886                      Network                                
Name
Glutamate transport in synapse
Definition
Glutamine -- GLS -> Glutamate(cyto) -- vGLUT -> Glutamate(vesicular)
  Expanded
C00064 -- (2744,27165) -> C00025 -- (57030,57084,246213) -> C00025
Class
nt06544 Neuroactive ligand signaling
Type
Reference
Pathway
hsa04724  Glutamatergic synapse
hsa04082  Neuroactive ligand signaling
Gene
2744  GLS; glutaminase
27165  GLS2; glutaminase 2
57030  SLC17A7; solute carrier family 17 member 7
57084  SLC17A6; solute carrier family 17 member 6
246213  SLC17A8; solute carrier family 17 member 8
Metabolite
C00064  L-Glutamine
C00025  L-Glutamate
Reference
  Authors
Gass JT, Olive MF
  Title
Glutamatergic substrates of drug addiction and alcoholism.
  Journal
Biochem Pharmacol 75:218-65 (2008)
DOI:10.1016/j.bcp.2007.06.039
Reference
  Authors
Pagonabarraga J, Tinazzi M, Caccia C, Jost WH
  Title
The role of glutamatergic neurotransmission in the motor and non-motor symptoms in Parkinson's disease: Clinical cases and a review of the literature.
  Journal
J Clin Neurosci 90:178-183 (2021)
DOI:10.1016/j.jocn.2021.05.056
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