KEGG   NETWORK: N01907
Entry
N01907                      Network                                
Name
Transport of chloride, GLR
Definition
Glycine -> GLR -> Cl-
  Expanded
C00037 -> (2741,8001,2743) -> C00698
Class
nt06544 Neuroactive ligand signaling
Type
Reference
Pathway
hsa04082  Neuroactive ligand signaling
Gene
2741  GLRA1; glycine receptor alpha 1
8001  GLRA3; glycine receptor alpha 3
2743  GLRB; glycine receptor beta
Metabolite
C00037  Glycine
C00698  Cl-
Reference
  Authors
Shimizu-Okabe C, Kobayashi S, Kim J, Kosaka Y, Sunagawa M, Okabe A, Takayama C
  Title
Developmental Formation of the GABAergic and Glycinergic Networks in the Mouse Spinal Cord.
  Journal
Int J Mol Sci 23:ijms23020834 (2022)
DOI:10.3390/ijms23020834
Reference
  Authors
Zeilhofer HU, Werynska K, Gingras J, Yevenes GE
  Title
Glycine Receptors in Spinal Nociceptive Control-An Update.
  Journal
Biomolecules 11:846 (2021)
DOI:10.3390/biom11060846
Reference
  Authors
Harvey RJ, Yee BK
  Title
Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain.
  Journal
Nat Rev Drug Discov 12:866-85 (2013)
DOI:10.1038/nrd3893
Reference
  Authors
Zeilhofer HU, Acuna MA, Gingras J, Yevenes GE
  Title
Glycine receptors and glycine transporters: targets for novel analgesics?
  Journal
Cell Mol Life Sci 75:447-465 (2018)
DOI:10.1007/s00018-017-2622-x
Reference
  Authors
Harvey RJ, Carta E, Pearce BR, Chung SK, Supplisson S, Rees MI, Harvey K
  Title
A critical role for glycine transporters in hyperexcitability disorders.
  Journal
Front Mol Neurosci 1:1 (2008)
DOI:10.3389/neuro.02.001.2008
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