KEGG   NETWORK: N01942
Entry
N01942                      Network                                
Name
SLIT-ROBO signaling in neuron
Definition
SLIT1/2 == ROBO1/2 -> (SRGAP,ABL1,AKT)
  Expanded
6585,9353 == 6091,6092 -> ((57522,23380,9901,393),25,(207,208,10000))
Class
nt06546 IgSF CAM signaling
Type
Reference
Pathway
hsa04517 IGSF CAM signaling   
Gene
6585  SLIT1; slit guidance ligand 1
9353  SLIT2; slit guidance ligand 2
6091  ROBO1; roundabout guidance receptor 1
6092  ROBO2; roundabout guidance receptor 2
57522  SRGAP1; SLIT-ROBO Rho GTPase activating protein 1
23380  SRGAP2; SLIT-ROBO Rho GTPase activating protein 2
9901  SRGAP3; SLIT-ROBO Rho GTPase activating protein 3
393  ARHGAP4; Rho GTPase activating protein 4
25  ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
207  AKT1; AKT serine/threonine kinase 1
208  AKT2; AKT serine/threonine kinase 2
10000  AKT3; AKT serine/threonine kinase 3
Reference
  Authors
Bisiak F, McCarthy AA
  Title
Structure and Function of Roundabout Receptors.
  Journal
Subcell Biochem 93:291-319 (2019)
DOI:10.1007/978-3-030-28151-9_9
Reference
  Authors
Tong M, Jun T, Nie Y, Hao J, Fan D
  Title
The Role of the Slit/Robo Signaling Pathway.
  Journal
J Cancer 10:2694-2705 (2019)
DOI:10.7150/jca.31877
Reference
  Authors
Ballard MS, Hinck L
  Title
A roundabout way to cancer.
  Journal
Adv Cancer Res 114:187-235 (2012)
DOI:10.1016/B978-0-12-386503-8.00005-3
Reference
  Authors
Blockus H, Chedotal A
  Title
Slit-Robo signaling.
  Journal
Development 143:3037-44 (2016)
DOI:10.1242/dev.132829
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