KEGG   NETWORK: N01943
Entry
N01943                      Network                                
Name
SLIT-ROBO signaling in podocyte
Definition
SLIT2 == ROBO2 -| (NPHS1+NCK1) -> (WASL+PAK) -> (ACTB,ACTG1)
  Expanded
9353 == 6092 -| (4868+4690) -> (8976+(5058,5062,5063)) -> (60,71)
Class
nt06546 IgSF CAM signaling
Type
Reference
Pathway
hsa04517 IGSF CAM signaling   
Gene
9353  SLIT2; slit guidance ligand 2
6092  ROBO2; roundabout guidance receptor 2
4868  NPHS1; NPHS1 adhesion molecule, nephrin
4690  NCK1; NCK adaptor protein 1
8976  WASL; WASP like actin nucleation promoting factor
5058  PAK1; p21 (RAC1) activated kinase 1
5062  PAK2; p21 (RAC1) activated kinase 2
5063  PAK3; p21 (RAC1) activated kinase 3
60  ACTB; actin beta
71  ACTG1; actin gamma 1
Reference
  Authors
Feng L, Shu HP, Sun LL, Tu YC, Liao QQ, Yao LJ
  Title
Role of the SLIT-ROBO signaling pathway in renal pathophysiology and various renal diseases.
  Journal
Front Physiol 14:1226341 (2023)
DOI:10.3389/fphys.2023.1226341
LinkDB

DBGET integrated database retrieval system