KEGG   NETWORK: N02008
Entry
N02008                      Network                                
Name
Desmosome maturation
Definition
DSC/DSG == DSC/DSG -> (PKP+JUP) -> DSP -> (KRT1/2,DES,VIM)
  Expanded
((1823,1824,1825),(1828,1829,1830,147409)) == ((1823,1824,1825),(1828,1829,1830,147409)) -> ((5317,5318,11187)+3728) -> 1832 -> (3848,3849,1674,7431)
Class
nt06549 Cadherin signaling
Type
Reference
Pathway
hsa04519 Cadherin signaling   
Gene
1823  DSC1; desmocollin 1
1824  DSC2; desmocollin 2
1825  DSC3; desmocollin 3
1828  DSG1; desmoglein 1
1829  DSG2; desmoglein 2
1830  DSG3; desmoglein 3
147409  DSG4; desmoglein 4
5317  PKP1; plakophilin 1
5318  PKP2; plakophilin 2
11187  PKP3; plakophilin 3
3728  JUP; junction plakoglobin
1832  DSP; desmoplakin
3848  KRT1; keratin 1
3849  KRT2; keratin 2
1674  DES; desmin
7431  VIM; vimentin
Reference
PMID:15819402
  Authors
Cheng X, Den Z, Koch PJ
  Title
Desmosomal cell adhesion in mammalian development.
  Journal
Eur J Cell Biol 84:215-23 (2005)
DOI:10.1016/j.ejcb.2004.12.008
Reference
PMID:21508970
  Authors
Dusek RL, Attardi LD
  Title
Desmosomes: new perpetrators in tumour suppression.
  Journal
Nat Rev Cancer 11:317-23 (2011)
DOI:10.1038/nrc3051
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