KEGG   REACTION: R00087
Entry
R00087                      Reaction                               
Name
ATP diphosphohydrolase (diphosphate-forming);
ATP pyrophosphohydrolase
Definition
ATP + H2O <=> AMP + Diphosphate
Equation
C00002 + C00001 <=> C00020 + C00013
Comment
the first step of two-step reaction (see R13610, R00087+R16308+R13609)
Reaction class
RC00002  C00002_C00020
Enzyme
3.6.1.8         3.6.1.9         4.2.1.186
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
rn01232  Nucleotide metabolism
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.8
     R00087  ATP + H2O <=> AMP + Diphosphate
    3.6.1.9
     R00087  ATP + H2O <=> AMP + Diphosphate
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.186
     R00087  ATP + H2O <=> AMP + Diphosphate
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.6.1.9
   R01532  Nucleoside triphosphate <=> Nucleotide
    R00087  ATP <=> AMP
Orthology
K01513  ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K04765  nucleoside triphosphate diphosphatase [EC:3.6.1.9]
Other DBs
RHEA: 14248
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