KEGG REACTION: R00191

REACTION: R00191

Entry

R00191                      Reaction

Name

adenosine 3',5'-phosphate 5'-nucleotidohydrolase

Definition

3',5'-Cyclic AMP + H2O <=> AMP

Equation

C00575 + C00001 <=> C00020

Reaction class

RC00296

C00020_C00575

Enzyme

3.1.4.17 3.1.4.53

Pathway

rn00230

Purine metabolism

rn01100

Metabolic pathways

Brite

Enzymatic reactions [BR:br08201]
3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17
     R00191  3',5'-Cyclic AMP + H2O <=> AMP
    3.1.4.53
     R00191  3',5'-Cyclic AMP + H2O <=> AMP
IUBMB reaction hierarchy [BR:br08202]
3. Hydrolase reactions
  3.1.4.17
   R03259  3',5'-Cyclic nucleotide <=> Nucleoside 5'-phosphate
    R00191  3',5'-Cyclic AMP <=> AMP

Orthology

K01120

3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17]

K03651

3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]

K13293

cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]

K13294

cAMP-specific phosphodiesterase [EC:3.1.4.53]

K13296

cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]

K13298