KEGG   REACTION: R01454
Entry
R01454                      Reaction                               
Name
Cholesterol:oxygen oxidoreductase (side-chain-cleaving)
Definition
Cholesterol + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 20alpha-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
Equation
C00187 + C00007 + 2 C00080 + 2 C00662 <=> C05500 + C00001 + 2 C00667
Comment
first step of R02724 (R01454+R04854+R03933)
Reaction class
RC00521  C00187_C05500
Enzyme
1.14.15.6
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Orthology
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
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