REACTION: R01457
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Entry
R01457 Reaction
Name
cholesterol:NADP+ Delta24-oxidoreductase
Definition
Cholesterol + NADP+ <=> Desmosterol + H+ + NADPH
Equation
C00187
+
C00006
<=>
C01802
+
C00080
+
C00005
Reaction class
RC00001
C00005_C00006
RC00522
C00187_C01802
Enzyme
1.3.1.72
Pathway
rn00100
Steroid biosynthesis
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.72
R01457 Cholesterol + NADP+ <=> Desmosterol + H+ + NADPH
BRITE hierarchy
Orthology
K09828
Delta24-sterol reductase [EC:
1.3.1.72
1.3.1.-]
Other DBs
RHEA:
36394
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