REACTION: R01613
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Entry
R01613 Reaction
Name
malonyl-CoA:4-coumaroyl-CoA malonyltransferase(cyclizing)
Definition
p-Coumaroyl-CoA + 3 Malonyl-CoA <=> Naringenin chalcone + 4 CoA + 3 CO2
Equation
C00223
+ 3
C00083
<=>
C06561
+ 4
C00010
+ 3
C00011
Comment
multi-step reaction
Reaction class
RC00004
C00010_C00083 C00010_C00223
RC02726
C00223_C06561
Enzyme
2.3.1.74
Pathway
rn00941
Flavonoid biosynthesis
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Module
M00137
Flavanone biosynthesis, phenylalanine => naringenin
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.74
R01613 p-Coumaroyl-CoA + 3 Malonyl-CoA <=> Naringenin chalcone + 4 CoA + 3 CO2
BRITE hierarchy
Orthology
K00660
chalcone synthase [EC:
2.3.1.74
]
Other DBs
RHEA:
11131
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