KEGG   REACTION: R01938
Entry
R01938                      Reaction                               
Definition
2-Oxoadipate + Ammonia + NADP+ <=> 2-Aminomuconate + NADPH + H+ + H2O
Equation
C00322 + C00014 + C00006 <=> C02220 + C00005 + C00080 + C00001
Comment
NADH (see R01937)
possibly multi-step reaction
Reaction class
RC00001  C00005_C00006
RC00208  C00322_C02220
Enzyme
1.5.1.-
Pathway
rn00380  Tryptophan metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.-
     R01938  2-Oxoadipate + Ammonia + NADP+ <=> 2-Aminomuconate + NADPH + H+ + H2O
Reference
1  [PMID:14275129]
  Authors
NISHIZUKA Y, ICHIYAMA A, GHOLSON RK, HAYAISHI O.
  Title
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. I. ENZYMIC FORMATION OF GLUTARIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
  Journal
J Biol Chem 240:733-9 (1965)
DOI:10.1016/S0021-9258(17)45237-9
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