KEGG   REACTION: R02018
Entry
R02018                      Reaction                               
Name
2'-deoxyuridine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase
Definition
dUDP + Thioredoxin disulfide + H2O <=> Thioredoxin + UDP
Equation
Reaction class
RC00013  C00342_C00343
RC00613  C00015_C01346
Enzyme
Pathway
rn00240  Pyrimidine metabolism
rn01100  Metabolic pathways
rn01232  Nucleotide metabolism
Module
M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1
     R02018  dUDP + Thioredoxin disulfide + H2O <=> Thioredoxin + UDP
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.17.4.1
   R04294  2'-Deoxyribonucleoside diphosphate <=> Ribonucleoside diphosphate
    R02018  dUDP <=> UDP
Orthology
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
K00526  ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
K10807  ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808  ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
Other DBs
RHEA: 28029
LinkDB

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