KEGG   REACTION: R02237
Entry
R02237                      Reaction                               
Name
7,8-dihydropteroate:L-glutamate ligase (ADP-forming)
Definition
ATP + Dihydropteroate + L-Glutamate <=> ADP + Orthophosphate + Dihydrofolate
Equation
C00002 + C00921 + C00025 <=> C00008 + C00009 + C00415
Reaction class
RC00002  C00002_C00008
RC00064  C00025_C00415
RC00162  C00415_C00921
Enzyme
6.3.2.12        6.3.2.17
Pathway
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00126  Tetrahydrofolate biosynthesis, GTP => THF
M00840  Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF
M00841  Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12
     R02237  ATP + Dihydropteroate + L-Glutamate <=> ADP + Orthophosphate + Dihydrofolate
    6.3.2.17
     R02237  ATP + Dihydropteroate + L-Glutamate <=> ADP + Orthophosphate + Dihydrofolate
Orthology
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K20457  dihydrofolate synthase [EC:6.3.2.12]
K22099  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K24102  dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]
Other DBs
RHEA: 23587
LinkDB

DBGET integrated database retrieval system