KEGG   REACTION: R02521
Entry
R02521                      Reaction                               
Name
4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating)
Definition
3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> Homogentisate + CO2
Equation
Comment
multi-step reaction
Reaction class
RC00738  C00544_C01179
Enzyme
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00350  Tyrosine metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00044  Tyrosine degradation, tyrosine => homogentisate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.27
     R02521  3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> Homogentisate + CO2
Orthology
K00457  4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
Other DBs
RHEA: 16192
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