KEGG REACTION: R02550

REACTION: R02550

Entry

R02550                      Reaction

Name

toluene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating);
toluene/o-xylene monooxygenase

Definition

Benzyl alcohol + 2 Oxidized ferredoxin + H2O <=> Toluene + Oxygen + 2 Reduced ferredoxin + 2 H+

Equation

C00556 + 2 C00139 + C00001 <=> C01455 + C00007 + 2 C00138 + 2 C00080

Comment

Oxidized ferredoxin is re-reduced by NADH (see R05875)

Reaction class

RC00269

C00556_C01455

Enzyme

1.14.13.- 1.14.15.26

Pathway

rn00623

Toluene degradation

rn01100

Metabolic pathways

rn01120

Microbial metabolism in diverse environments

rn01220

Degradation of aromatic compounds

Module

M00538

Toluene degradation, toluene => benzoate

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-
     R02550  Benzyl alcohol + 2 Oxidized ferredoxin + H2O <=> Toluene + Oxygen + 2 Reduced ferredoxin + 2 H+
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.26
     R02550  Benzyl alcohol + 2 Oxidized ferredoxin + H2O <=> Toluene + Oxygen + 2 Reduced ferredoxin + 2 H+

Orthology

K15757

toluene methyl-monooxygenase [EC:1.14.15.26]

K15758

toluene methyl-monooxygenase electron transfer component [EC:1.18.1.3]

K15760

toluene monooxygenase system protein A [EC:1.14.13.236 1.14.13.-]

K15761

toluene monooxygenase system protein B [EC:1.14.13.236 1.14.13.-]

K15762

toluene monooxygenase system ferredoxin subunit

K15763