REACTION: R02723
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Entry
R02723 Reaction
Definition
Cholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 22(R)-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin
Equation
C00187
+
C00007
+ 2
C00662
+ 2
C00080
<=>
C05502
+
C00001
+ 2
C00667
Comment
first step of
R02724
(
R02723+R04855+R03933
)
Reaction class
RC00773
C00187_C05502
Enzyme
1.14.15.6
Pathway
rn00140
Steroid hormone biosynthesis
rn01100
Metabolic pathways
Module
M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Orthology
K00498
cholesterol monooxygenase (side-chain-cleaving) [EC:
1.14.15.6
]
Other DBs
RHEA:
34338
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