REACTION: R02810
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Entry
R02810 Reaction
Name
iodide:hydrogen-peroxide oxidoreductase
Definition
2 Iodide + Hydrogen peroxide + 2 H+ <=> Iodine + 2 H2O
Equation
2
C00708
+
C00027
+ 2
C00080
<=>
C01382
+ 2
C00001
Comment
thyroid peroxidase, TPO
multi-step reaction on thyroglobulin [KO:
K10809
] (see
R02810+R08520+R08521+R08522+R08523
)
Reaction class
RC00783
C00708_C01382
Enzyme
1.11.1.8
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8
R02810 2 Iodide + Hydrogen peroxide + 2 H+ <=> Iodine + 2 H2O
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RHEA:
23339
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REACTION: R08520
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Entry
R08520 Reaction
Definition
[Thyroglobulin]-L-tyrosine + Iodine <=> [Thyroglobulin]-3-iodo-L-tyrosine + Hydroiodic acid
Equation
C16733
+
C01382
<=>
C16732
+
C05590
Comment
thyroid peroxidase, TPO
following after
R02810
subsequently
R08521 or R08522
Reaction class
RC00949
C16732_C16733
Enzyme
1.11.1.8
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8
R08520 [Thyroglobulin]-L-tyrosine + Iodine <=> [Thyroglobulin]-3-iodo-L-tyrosine + Hydroiodic acid
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