KEGG   REACTION: R03067
Entry
R03067                      Reaction                               
Name
(7,8-dihydropterin-6-yl)methyl diphosphate:4-aminobenzoate 2-amino-4-hydroxy-7,8-dihydropteridine-6-methenyltransferase
Definition
6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-Aminobenzoate <=> Diphosphate + Dihydropteroate
Equation
C04807 + C00568 <=> C00013 + C00921
Reaction class
RC00121  C00568_C00921
Enzyme
2.5.1.15
Pathway
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00126  Tetrahydrofolate biosynthesis, GTP => THF
M00840  Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF
M00841  Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.15
     R03067  6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-Aminobenzoate <=> Diphosphate + Dihydropteroate
Orthology
K00796  dihydropteroate synthase [EC:2.5.1.15]
K13939  dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:4.1.2.25 2.7.6.3 2.5.1.15]
K13941  2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15]
K18824  dihydropteroate synthase type 2 [EC:2.5.1.15]
K18825  dihydropteroate synthase type 3 [EC:2.5.1.15]
K18974  dihydropteroate synthase type 1 [EC:2.5.1.15]
K24102  dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]
Other DBs
RHEA: 19952
LinkDB

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