KEGG   REACTION: R03713
Entry
R03713                      Reaction                               
Name
11beta,21-dihydroxy-3,20-oxo-5beta-pregnan-18-al:NADP+ delta4-oxidoreductase
Definition
11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADP+ <=> Aldosterone + NADPH + H+
Equation
C05473 + C00006 <=> C01780 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00145  C01780_C05473
Enzyme
1.3.1.3
Pathway
rn00140  Steroid hormone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.3
     R03713  11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADP+ <=> Aldosterone + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.3.1.3
   R13168  3-Oxo-5beta-steroid <=> 3-Oxo-Delta4-steroid
    R03713  11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al <=> Aldosterone
Orthology
K00251  3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
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