KEGG   REACTION: R03874
Entry
R03874                      Reaction                               
Name
[peptide]-(2S)-2-hydroxyglycine peptidyl-amide-lyase (glyoxylate-forming)
Definition
[Peptide]-(2S)-2-hydroxyglycine <=> [Peptide]-amide + Glyoxylate
Equation
C03303 <=> C02179 + C00048
Reaction class
RC00153  C00048_C03303
RC00379  C02179_C03303
Enzyme
4.3.2.5
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.3  Carbon-nitrogen lyases
   4.3.2  Amidine-lyases
    4.3.2.5
     R03874  [Peptide]-(2S)-2-hydroxyglycine <=> [Peptide]-amide + Glyoxylate
Orthology
K18200  peptidylamidoglycolate lyase [EC:4.3.2.5]
Reference
1  [PMID:2207061]
  Authors
Katopodis AG, Ping D, May SW.
  Title
A novel enzyme from bovine neurointermediate pituitary catalyzes dealkylation of alpha-hydroxyglycine derivatives, thereby functioning sequentially with peptidylglycine alpha-amidating monooxygenase in peptide amidation.
  Journal
Biochemistry 29:6115-20 (1990)
DOI:10.1021/bi00478a001
Other DBs
RHEA: 20927
LinkDB

DBGET integrated database retrieval system