KEGG   REACTION: R04199
Entry
R04199                      Reaction                               
Name
2,3,4,5-tetrahydrodipicolinate:NADP+ 4-oxidoreductase
Definition
2,3,4,5-Tetrahydrodipicolinate + NADP+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+
Equation
C03972 + C00006 + C00001 <=> C20258 + C00005 + C00080
Comment
NAD+ (see R04198)
Reaction class
RC00001  C00005_C00006
RC00478  C03972_C20258
Enzyme
1.17.1.8
Pathway
rn00261  Monobactam biosynthesis
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
Module
M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00525  Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526  Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.1  With NAD+ or NADP+ as acceptor
    1.17.1.8
     R04199  2,3,4,5-Tetrahydrodipicolinate + NADP+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+
Orthology
K00215  4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
Other DBs
RHEA: 35334
LinkDB

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