KEGG   REACTION: R05224
Entry
R05224                      Reaction                               
Definition
Hydrogenobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Hydrogenobyrinate a,c diamide + 2 Orthophosphate + 2 L-Glutamate + 2 ADP
Equation
C06399 + 2 C00064 + 2 C00002 + 2 C00001 <=> C06503 + 2 C00009 + 2 C00025 + 2 C00008
Comment
multi-step reaction
Reaction class
RC00002  C00002_C00008
RC00010  C00025_C00064
RC01301  C06399_C06503
Enzyme
6.3.5.9
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00925  Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
Orthology
K02224  cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
Other DBs
RHEA: 12547
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