REACTION: R05547
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Entry
R05547 Reaction
Definition
N1-Amidinostreptamine 6-phosphate + L-Arginine <=> Streptidine 6-phosphate + L-Ornithine
Equation
C11351
+
C00062
<=>
C01121
+
C00077
Comment
StrB1/2
Reaction class
RC00024
C00062_C00077
RC00939
C01121_C11351
Pathway
rn00521
Streptomycin biosynthesis
rn01110
Biosynthesis of secondary metabolites
Reference
1 [PMID:
9922132
]
Authors
Fritsche E, Bergner A, Humm A, Piepersberg W, Huber R
Title
Crystal structure of L-arginine:inosamine-phosphate amidinotransferase StrB1 from Streptomyces griseus: an enzyme involved in streptomycin biosynthesis.
Journal
Biochemistry 37:17664-72 (1998)
DOI:
10.1021/bi981949p
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