KEGG   REACTION: R05815
Entry
R05815                      Reaction                               
Name
cobyrinate:L-glutamine amido-ligase (ADP-forming)
Definition
Cobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Cob(II)yrinate a,c diamide + 2 L-Glutamate + 2 ADP + 2 Orthophosphate
Equation
C05773 + 2 C00064 + 2 C00002 + 2 C00001 <=> C06504 + 2 C00025 + 2 C00008 + 2 C00009
Comment
two-step reaction (see R09598+R09599)
Reaction class
RC00002  C00002_C00008
RC00010  C00025_C00064
RC01301  C05773_C06504
Enzyme
6.3.5.11
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.11
     R05815  Cobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Cob(II)yrinate a,c diamide + 2 L-Glutamate + 2 ADP + 2 Orthophosphate
Orthology
K02224  cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
Other DBs
RHEA: 26292
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