KEGG   REACTION: R06449
Entry
R06449                      Reaction                               
Definition
5-O-beta-D-Mycaminosyltylactone + 2 NADPH + 2 Oxygen + 2 H+ <=> 20-Oxo-5-O-beta-mycaminosyltylactone + 2 NADP+ + 3 H2O
Equation
C12001 + 2 C00005 + 2 C00007 + 2 C00080 <=> C20760 + 2 C00006 + 3 C00001
Comment
cytochrome P450,TylI
multi-step reaction
Reaction class
RC00001  C00005_C00006
RC03223  C12001_C20760
Pathway
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00773  Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin
Orthology
K15992  cytochrome P450 TylI
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