REACTION: R06465
Help
Entry
R06465 Reaction
Definition
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2a'' aglycone + NADP+ + H2O
Equation
C11969
+
C00005
+
C00007
<=>
C11970
+
C00006
+
C00001
Comment
cytochrome P450 hydroxylase,AveE
Reaction class
RC00001
C00005_C00006
RC01527
C11969_C11970
Enzyme
1.14.-.-
Pathway
rn00522
Biosynthesis of 12-, 14- and 16-membered macrolides
Orthology
K14372
cytochrome P450 hydroxylase [EC:1.14.-.-]
LinkDB
All DBs
DBGET
integrated database retrieval system