 | | REACTION: R06473 | |
| Entry |
|
|---|
| Definition |
5-Oxoavermectin ''1a'' aglycone + NADPH + H+ <=> Avermectin B1a aglycone + NADP+
|
|---|
| Equation |
|
|---|
|
 |
|---|
| Comment |
C-5 ketoreductase,AveF
|
|---|
| Reaction class |
|
|---|
| Pathway |
| rn00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
| rn01110 | Biosynthesis of secondary metabolites |
|
|---|
| Module |
| M00777 | Avermectin biosynthesis, 2-methylbutanoyl-CoA/isobutyryl-CoA => 6,8a-Seco-6,8a-deoxy-5-oxoavermectin 1a/1b aglycone => avermectin A1a/B1a/A1b/B1b |
|
|---|
| Orthology |
|
|---|
| LinkDB |
|
|---|
|
|