KEGG   REACTION: R07169
Entry
R07169                      Reaction                               
Name
(R)-tetrahydroberberine:NADP+ oxidoreductase
Definition
(R)-Canadine + 2 NADP+ <=> Berberine + 2 NADPH + 2 H+
Equation
C11818 + 2 C00006 <=> C00757 + 2 C00005 + 2 C00080
Reaction class
RC00001  C00005_C00006
RC00798  C00757_C11818
Enzyme
1.5.1.31
Pathway
rn00950  Isoquinoline alkaloid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.31
     R07169  (R)-Canadine + 2 NADP+ <=> Berberine + 2 NADPH + 2 H+
Other DBs
RHEA: 21271
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