REACTION: R07604
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Entry
R07604 Reaction
Definition
2-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
Equation
C15978
+
C15972
<=>
C15979
+
C00068
Comment
Oxo-acid dehydrogenase complexes (see
R04225
), following after
R07603
Reaction class
RC00027
C00068_C15978
RC00627
C15972_C15979
RC02953
C15978_C15979
Enzyme
1.2.4.4
Pathway
rn00280
Valine, leucine and isoleucine degradation
Orthology
K00166
2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:
1.2.4.4
]
K00167
2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:
1.2.4.4
]
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
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integrated database retrieval system
