KEGG   REACTION: R08249
Entry
R08249                      Reaction                               
Name
N-acetylisoniazid amidohydrolase
Definition
N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid
Equation
C07585 + C00001 <=> C07447 + C07446
Comment
hepatic amidase
carboxylesterases (ec 3.1.1.1) also have some amidohydrolase activities
Reaction class
RC00162  C07446_C07585
RC00962  C07447_C07585
Enzyme
3.1.1.1         3.5.1.-
Pathway
rn00983  Drug metabolism - other enzymes
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.1
     R08249  N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.-
     R08249  N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid
Orthology
K01044  carboxylesterase 1 [EC:3.1.1.1]
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