KEGG   REACTION: R08258
Entry
R08258                      Reaction                               
Definition
NPC + H2O <=> SN-38 + 4-Amino-1-piperidinecarboxylic acid
Equation
C16543 + C00001 <=> C11173 + C16837
Comment
carboxylesterase
Reaction class
RC00475  C16543_C16837
RC00476  C11173_C16543
Enzyme
3.1.1.1
Pathway
rn00983  Drug metabolism - other enzymes
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.1
     R08258  NPC + H2O <=> SN-38 + 4-Amino-1-piperidinecarboxylic acid
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.1.1.1
   R00630  Ester <=> Alcohol
    R08258  NPC <=> SN-38
Orthology
K01044  carboxylesterase 1 [EC:3.1.1.1]
K03927  carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56]
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