KEGG   REACTION: R08663
Entry
R08663                      Reaction                               
Name
L-valine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
L-Valine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-2-Methylpropanal oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C00183 + 2 C00007 + 2 C03024 <=> C03219 + 2 C03161 + C00011 + 3 C00001
Comment
three-step reaction (see R10031+R10032+R10033)
The enzyme can also accept L-isoleucine as substrate, with a lower activity.(1.14.14.39)
3step reaction (similar to R00730+R04460+R07190)
Reaction class
RC00001  C00005_C00006
RC02339  C00183_C03219
Enzyme
1.14.14.38
Pathway
rn00966  Glucosinolate biosynthesis
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.38
     R08663  L-Valine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-2-Methylpropanal oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Orthology
K13401  valine N-monooxygenase [EC:1.14.14.38]
Other DBs
RHEA: 28609
LinkDB

KEGG   RCLASS: RC02339
Entry
RC02339                     RClass                                 
Definition
C1c-C2b:C6a-*:C1c+N1a-C1c+N2b
N1a-N2b:*-O1b:C1c-C2b
Reactant pair
C00183_C03219    C00407_C19491
Related class
Reaction
R08663 R09403
Enzyme
1.14.14.38      1.14.14.39
Pathway
rn00966  Glucosinolate biosynthesis
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM030  Glucosinolate synthesis
Orthology
K13401  valine N-monooxygenase [EC:1.14.14.38]
K14984  isoleucine N-monooxygenase [EC:1.14.14.39]

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