KEGG   REACTION: R09512
Entry
R09512                      Reaction                               
Name
9H-carbazole,NADPH:oxygen oxidoreductase (2,3-hydroxylating)
Definition
Carbazole + NADPH + H+ + Oxygen <=> 2'-Aminobiphenyl-2,3-diol + NADP+
Equation
C08060 + C00005 + C00080 + C00007 <=> C08061 + C00006
Comment
NADH (see R05414)
Reaction class
RC00001  C00005_C00006
RC01370  C08060_C08061
Enzyme
1.14.12.22
Pathway
rn00621  Dioxin degradation
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00544  Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.22
     R09512  Carbazole + NADPH + H+ + Oxygen <=> 2'-Aminobiphenyl-2,3-diol + NADP+
Orthology
K15751  carbazole 1,9a-dioxygenase [EC:1.14.12.22]
K15752  carbazole 1,9a-dioxygenase ferredoxin component
K15753  carbazole 1,9a-dioxygenase ferredoxin reductase component
Other DBs
RHEA: 27845
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