KEGG   REACTION: R09990
Entry
R09990                      Reaction                               
Name
L-threo-tetrahydrobiopterin:NADP+ oxidoreductase
Definition
L-threo-Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H+
Equation
C20264 + 2 C00006 <=> C03684 + 2 C00005 + 2 C00080
Reaction class
RC00001  C00005_C00006
RC02162  C03684_C20264
Enzyme
1.1.1.325
Pathway
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00843  L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.325
     R09990  L-threo-Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H+
Orthology
K17745  sepiapterin reductase [EC:1.1.1.325]
Other DBs
RHEA: 32626
LinkDB

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