KEGG   REACTION: R11050
Entry
R11050                      Reaction                               
Definition
(R)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide
Equation
C03043 + C00007 <=> C21075 + C00027
Comment
first step of two-step reaction (see R07170, R11050+R11049)
Reaction class
RC02755  C00007_C00027
RC03336  C03043_C21075
Enzyme
1.5.3.6
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00810  Nicotine degradation, pyridine pathway, nicotine => 2,6-dihydroxypyridine/succinate semialdehyde
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.5  Acting on the CH-NH group of donors
   1.5.3  With oxygen as acceptor
    1.5.3.6
     R11050  (R)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide
Orthology
K19890  (R)-6-hydroxynicotine oxidase [EC:1.5.3.6]
Other DBs
RHEA: 46991
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